Arylsulfatase A-deficient mice

Metachromatic leukodystrophy (MLD) is a lysosomal storage disorder caused by the deficiency of arylsulfatase A (ASA).

Artificial Interferons

Interferons are a family of proteins that were originally named for their ability to interfere with viral replication and propagation. To date, it is known that interferons are also involved in combating bacterial and parasitic infections, inhibit cell division, and promote or impede the differentiation of cells.

Encrypted Cooperative Control

Cooperative control in multi-agent systems enable the implementation of a "global" objective through the use of "local" regulatory strategies in networked systems.

Double face with high efficiency

This invention describes a process and a device for the production of double-face knitted fabrics using a double plating technique.

PICOihc

The invention pertains to an integrate-and-hold circuit which is used as a sampler. The typical structure of an integrate-and-hold circuit (IHC) is a multiplier serving as a switch followed by a resettable integrator with a hold capacitor.

Stable Position Of Sound Sources

Scientists at RWTH Aachen University recently developed a method for dynamic adaptation of binaural headphone reproduction to head movements of users.

Protective cover made of yeast

Yeast cells are a by-product of beer and bioethanol production and are therefore readily available.

MIRVAD

Post-operative right heart failure may develop in more than 40% of patients undergoing implantation of a left ventricular assist device (L-VAD) and cardiac transplantation.

Trityl radicals

Scientists at the University of Bielefeld developed asymmetric derivates of the so called Finland-Trityls for spectroscopic and analytical use.

Novel therapeutic for MLD

Metachromatic leukodystrophy (MLD) is a genetic lysosomal accumulation disease caused by the deficiency of the enzymatic activity of arylsulfatase A (ASA).

HoWirk

The invention in question here is a high-speed knitting process.

Recycled yarn

This invention describes a recyclable cotton yarn. The fiber length of conventional yarns is shortened by the recycling process to such an extent that these yarns can no longer be reused for high-quality textile products.

RFswitch

This invention describes an extended radio-frequency switch (E-RFS) with improved insulation properties, consisting of a conventional switch (RFS) and an electronic network, in which the electronic network is connected in parallel to the RFS when this is in the off state.

Adhesives from lactic acid

The invention concerns the production of special copolymers based on poly-L-lactide (PLLA) and formulations of hot-melt pressure sensitive adhesives based on them.

Maintaining polarization in optical fibers (PoF)

Apparatus and method for precisely maintaining the linear polarization of light at the output of an optical fiber

UHV-glass cell

The invention consists of a glass cell characterized by an outstanding value of birefringence (around 10–8) with an extensive optical access due to its dodecagonal shape.

Aptamer D3P-21

Prostate cancer is the most common cancer among men. In particular, hormone refractory prostate cancer is not curable and targeted therapies are yet not available.

Poly(vinylphenothiazine)-cathodes

The presented invention describes a composite electrode for lithium-ion or redox flow batteries made of organic material with very high cycling stability.

RAD51C

Despite the rising knowledge about genes involved in the formation and occurrence of cancers, only a limited amount of genes has been identified to be involved in hereditary cancers, e.g. BRCA1, BRCA2.

odemS

Scientists of the Rheinische Friedrich Wilhelms University of Bonn and the Max Planck Gesellschaft developed a modular sensor system for online detection of Triacetontriperoxide (TATP) in gas phase. The detection took place in open air flow.

Adaptive Controller

Dynamic systems often use a two-position controller and a simple sensor that only indicates whether a threshold is exceeded or not.

Cleaning robot swarm

Particularly in the commercial sector (e.g. hotels, offices, retirement homes, hospitals) but also in private use, it is desirable if a floor cleaning by robots in the shortest possible time is completed (noise, accessibility).

Drivetrain Integrated DC-DC Converter for Multiple Voltage Level Vehicles

Hybrid vehicles of the new generation use two different voltage networks. The starter and other high power components are primarily powered by the higher voltage (48 V) battery.

Dynamic Range Extender

The present invention describes a device for the recovery of electrical energy from electromagnetic radiation. To power electronic devices, there are different approaches.

DynLinkwitz

Loudspeaker enclosures for low frequency reproduction face the developer with a goal conflict. Either he achieves a small volume enclosure or he achieves a low cutoff frequency.

Antireflective integrated optical waveguide

In transitions between dielectric optical waveguides of different thickness, it comes through modal mismatch usually to radiation losses and optical backscatter.

MMOUE

MMOUE is an optical data transmission system, which uses in addition to the wavelength division multiplexing a mode multiplexing in order to increase the transmission rate.

Air-Retaining-Grids

The present invention "Air-Retaining Grids Technology" describes a new possibility for the architecture and construction of surfaces which are able to keep a layer of gas stable even under changing pressure conditions when immersed in liquid. Structured, non-wettable surfaces are used for various applications, for example as self-cleaning surfaces.

OsteoProtect

There are currently 200 million people suffering from osteoporosis worldwide. Low bone mass and deteriorating bone quality lead to an increased risk of fractures, high morbidity and increased mortality.

Ligand-free production of gold nanoparticles

The invention related to a process for the preparation of ligand-free gold nanoparticles (Au-NP).

Rotary piston pump

So far, the problem of sealing has been a major challenge when using rotary piston pumps.

Non-random chitosans

Chitosans are a family of functional biopolymers, typically produced by partial de-N-acetylation of chitin, one of the most abundant biopolymers in the world.

SUpDEq

Headphone-based binaural 3D audio gives us a realistic sound experience that can be enhanced even further by considering the head movements of the listener.

MPTSC

For a fast and precise control of mechatronic systems usually non-linear PID controllers are used. The more nonlinearities a system contains, the more complex the control task becomes.

Plasmasensor

Plasmas are used in many technical fields. For instance, plasma assisted technologies are used to modify, clean or coat surfaces.

TDTO (Three- Dimensional Titanium Oxide)

The present invention belongs to the technical field of rechargeable batteries and supercapacitors. Particularly, it relates to an electrode material for rechargeable batteries and electrochemical capacitors, a method for preparing the same, and rechargeable batteries as well as electrochemical capacitors.

Anode Material for Lithium-Ion Batteries

The presented technology offers methods for the synthesis and preparation of carbon coated metal oxide nanoparticles for application as anodic materials in lithium-ion batteries.

Malignancy marker for therapy planning

The diagnosis, classification and therapy of prostate cancer are based on the PSA value, the Gleason score from histology obtained by prostate biopsies and an imaging diagnosis from CT and bone scintigraphy.

EasyDMEK Shooter – PrepLoad-Tool

Corneal transplantation is the most frequently performed and most successful organ transplantion in medicine. Each layer of the cornea can develop its own disease.

Nano-Goethite blocker

Scientists at the University of Duisburg-Essen have developed a method for modifying the hydraulic conductivity of sedimentary or rock layers.

Induced Pluripotent Stem Cells (iPSC) of Patients with Heart Diseases

The iPSCs were generated from peripheral blood mononuclear cells(PBMCs) usingthenon-integrating CytoTune™-iPS 2.0 Sendai Reprogramming Kit.

Combinatory Asthma Endoytping Assay

Asthma is a disease of several subtypes characterized by different severity and a distinct immunological background. Most importantly, several subtypes of allergic asthma need to be correctly identified and distinguished from forms of non-allergic asthma.

Morphologic optimization of Fungi

Fungi play an important role in biotechnological processes for the production of organic acids, enzymes, antibiotics, polyols, vitamins, (glyco-)lipids, and a wide variety of other secondary metabolites.

Downstream processing of L-Tryptophan

L-Tryptophan is an essential amino acid, which e.g. is used as dietary supplement, as food additive and as a pharmaceutical. The synthesis is possible in different ways.

Click-Mass Spectrometry of lipids

Aberrations in fatty acid metabolism are associated with pathological states and have become a focus of current research, particularly due to the interest in metabolic overload diseases.

Protein delivery into cells by HTRA1

Precise and graded manipulation of protein levels in mammalian cells is an essential experimental tool in both basic research and clinical applications.

HTRA inhibitors

High Temperature Requirement A (HTRA) proteins are serine proteases of the S1 family (trypsin/chymotrypsin-like). HTRA1 is supposed to play a role in macular degeneration, and HTRA2 has been associated with cell death in reperfusion-ischemia.

Cartilage-specific antimicrobial CLEC3A

Preventing prostheses- and dental implant-associated infection using antimicrobial peptides of cartilage-specific CLEC3A

Individualize and thereby optimize radiotherapy

The success of radiotherapy decisively depends on how sensitive the tumour is to radiation.

Tool coils

Tool coils for or magneforming (or electromagnetic forming = EMF) of complex, 3D shaped parts were previously wound from wires or produced by complex processes such as milling and wire eroding.

Shell4Cell

Biological safety testing is required for air quality in the human environment such as cities, public buildings, and production sites for drugs and cosmetics, medical materials and for other applications.

x-PET

A process for the production of uniaxially oriented, high-modulus and high-strength PET (polyethylene terephthalate) or PBT (PBT = polybutylene terephthalate) profiles directly from the melt has been developed at the Technical University of Dortmund.

CLL diagonal

Scientists at FH Aachen - University of Applied Sciences have developed a wall element consisting of several layers of differently aligned woods, which not only provide the required load-bearing capacity but also the rigidity necessary for single-story and multistory constructions.

Diagnosis of osteoarthritis

Osteoarthritis (OA) is the most common degenerative disease of joints world-wide. About two-third of people over 65 years are affected, whereas the etiology is largely unclear.

O3Desi

Careful control of the patient's blood temperature is imperative in cardiac surgery. The heat exchangers used for this purpose are usually integrated in the oxygenator of the heart-lung machine.

CurrentShare

To reduce the input resistance of power modules, single semiconductor switches are usually connected in parallel.

ComNoEL

Due to the steadily increasing number of electrical and electronic devices in motor vehicles, there is an ever-increasing disturbance on the supply lines. In particular the power electronics generate unwanted interference signals.

Wireless Data Bus Bridge

At the Aachen University of Applied Science, a method for the transmission of data in a bus system was presented, which enables wireless communication between the bus users with the aid of a transceiver.

Brake resistor

To decelerate an electric motor, the remaining kinetic and magnetic energy must be removed from the system. This is usually done with brake resistors that convert the energy to heat.

Cyclic AMP Biosensor

Cyclic AMP is a key molecule in 2nd messenger cell signalling. Great effort has been taken to develop sensors that allow for noninvasive assessment of cAMP concentrations in living cells.

Efficient H2O decomposition

Due to the low overvoltages and excellent kinetics for the hydrogen evolution reaction, mainly precious metals such as Pt, Rh, Au and containing precious metal oxides such as RuO2 and RhxCr2-xO3 have been used as co-catalysts for photocatalytic hydrogen evolution.

Anti-tuberculosis drug

Tuberculosis resulting from infection with Mycobacterium tuberculosis (Mtb) is a serious global health problem accounting for 1.7 million deaths in 2016. A major reason for the high morbidity and mortality caused by Mtb is the long duration of therapy and increasing multidrug-resistance of Mtb strains.

Interlocksystem

For the safe operation of electrical systems, emergency stop or interlock applications interrupt the power supply or put the system in a safe state (DIN EN 60204-1 and DIN EN ISO 13850).

EF-Tu-binding Re-complexed antibiotics

A series of novel Re(I)-(CO)3-N-heterocyclic carbene (NHC) complexes bearing unsubstituted benzimidazol-2-ylidene ligands as well as a variety of bisimine ligands has been prepared and comprehensively characterised.

Opto-THC

Sample-and-hold circuits or track-and-hold (TH) circuits, along with analog-to-digital converters (ADCs), are the link from the analog to the digital world.

Vim3 and Mxi-2 Antibody

Kidney cancer is classified as malignant tumors originating from different renal cells with several subtypes. The cells of these subtypes can mimic a benign kidney tumor, called oncocytoma.

SMECS

The generation of cardiomyocytes (CMs) from pluripotent stem cells (PSCs) holds great promise for cardiac regenerative medicine.

Smart Adaptive Enhancer

A strong technological trend, particularly in robotics, in household appliance controls (smart home), and in the field of personal digital assistants, is voice control.

ITraRo

A method for the movement guidance of mobile robots by means of an intuitive trajectory control was recently developed at Bochum University for Applied Sciences.

Monitoring system for reinforced concrete

A variety of reinforced concrete factories are now affected by chloride-induced corrosion of the reinforcement.

sensDrill

The tool temperature has a great influence on the achievable quality and the tool wear during machining processes.

ET-CORMs

Carbon monoxide (CO), which is endogenously produced mainly in the course of heme degradation, was recently recognized as a powerful cytoprotective and homeostatic agent.

On-Board PSS Monitoring

The vehicle electrical system has become more and more complex over the years. Thus, the error probability increases, but an accurate fault identification and isolation becomes more and more difficult.

Novel Anti-Tuberculosis Compounds

Novel Mycobacterium tuberculosis thioredoxin reductase inhibitors with antimycobacterial activity in infected macrophages.

Vim3-based Fertility Diagnosis

Infertility affects an estimated 15 percent of couples globally, amounting to 48.5 million couples. Forty percent of cases are linked to men. An important factor of male infertility is an insufficient quality of sperms due to abnormal shape and/or motility.

Power factor correction as communication interface

In today's - and more important - in the future electricity grid, there will be an increasing number of small energy feeders, so that grid regulation becomes more complex.

TiDEC (OligoThymidine-initiated-DNA-Encoded)

The need of new drugs is high in many medical indications, for instance in oncology, and infectious diseases. However, the success rate of drug research and development has declined to unsustainable levels.

A Multifunctional Linker for CAR T-cells

A human CD34 hinge region allows detection as well as rapid CliniMACS-mediated enrichment of successfully engineered CAR-expressing immune effector cells and reduces adverse side-effects

ACDC-Control

In the transmission of electrical transmission lines, in which the overhead lines carry both AC and DC cables, special requirements arise for the protection concept. This applies in particular to contact errors between the alternating current and the direct current system.

A-l-a-din

The present invention focuses on a biocatalytic production process to aliphatic linear dinitriles, which avoids the need of hydrogen cyanide and leads to the desired products with excellent selectivity as in general no side-products were observed.

MOP

A new process for the formation of bi- or multi-axially oriented polymer structures has been developed.

FlexBend

Dünnwandige und biegeschlaffe Profile und Stabmaterialien können aus verschiedenen Gründen nicht mit konventionellen Verfahren gebogen werden, da hierbei Risse, Deformationen oder Falten entstehen würden.

CEACAM1 antibodies for anti-viral therapy

Cytotoxic CD8-positive T cells constitute the crucial leukocyte subpopulation for a cellular response against viral infection.

WOOD-INSERT

Scientists from the Ostwestfalen-Lippe University of Applied Sciences have developed a wood or wood-based material insert for the partial reinforcement of panel-shaped lightweight construction elements in sandwich construction that can be inserted using conventional tools, hand tools, machines or machining centers.

Ultrastiff Hydrogels

Today Hydrogels are widely used in membranes e.g. in seawater desalination plants. Conventional hydrogels, however, have very low stiffness and therefore have to be embedded in supporting structures. This is a complicated process and prevents the membranes from being cleaned when they are clogged with microorganisms.

WOOD-SPRING

Scientists at the Ostwestfalen-Lippe University of Applied Sciences have developed an inseparable connecting element for panel-shaped lightweight construction elements in sandwich construction, which can be used similarly to flat dowels for classic solid wood materials, including for sandwich elements.

HypoxieFit

Athletes, such as marathon runners and cyclists, often resort to training at higher altitude areas, in order to optimize their endurance. The atmosphere in such locations has lower oxygen content, which forces the human body to compensate for the reduced oxygen uptake by increasing hemoglobin concentration in blood.

CPAP-tubulin inhibitors

Centrosomes are major microtubule organizing centers in mammalian cells, which play a pivotal role in mitosis. Centrosome amplification is a hallmark of human cancers that can trigger cancer cell invasion.

IConEVe

IConEVe is a decentralized control system for electrically operated vehicles.

MOSi Anti-Fading Electrolyte Additives

Scientists of the MEET at Wilhelms University of Muenster developed a set of alkylsilyl complexes (MOSi) as elecrolyte additive, which enhance the performance of lithium ion batteries.

SkyrMem Skyrmion memoryr

Skyrmions are stable topological vortices in the magnetization. They can be created on surfaces of magnetic materials where they move through the materiallike a kind of hose.

VNA-Wheel Sensor

In today's passenger cars, a large number of sensors are installed which monitor the vehicle condition. For example, since 01.11.2014, all new cars have to be fitted with tire pressure sensors according to the EU regulation.

Open FET Sensor

The Open FET sensor is a field-effect-based sensor in which the gate electrode is connected only to the signal to be measured and not as usual to other electronic components.

WiMDaD Wire Mesh Damage Detection

Composite materials are nowadays used in many technical fields. Blades of wind power plants or aircraft parts, for example, are made out of these materials.

Biotechnological production of itaconic acid

Itaconic acid is one of the top bio-based chemical building blocks and thus a promising platform compound for the production of polymers, coatings, chemical compounds and biofuels.

Enantiomerically pure chiral N-acyl-a-aminonitriles

Enantiomerically pure N-acyl-a-aminonitriles gained these days interest in the pharmaceutical industry since a range of recently developed pharmaceuticals are based on this product class.

Liquid biopsy based early breast cancer detection

Early breast cancer detection, most favorably in a pre-cancerous (in situ) state is critical for the course of the disease and its outcome.

Click-SELEX

Selective Enhancement of Ligands by Exponential Enrichment (SELEX) has proven to be a powerful tool for idenfying functional oligonucleotides which bind to selected targets.

Aminolevulinic Acid from C1-Precursor

The production of aminolevulinic acid (ALA) is the first step in the biosynthesis of tetrapyrroles and porphyrines (like Chlorophyll, vitamin B12, heme).

Sili-Kill

A special process to coat SiO2 nanoparticles around with biocidal quaternary ammonium silanes has been achieved, so that the biocidal moiety points always outwards.

Full Inorganic Load Bearing Insulator

Scientists of the University of Duisburg-Essen developed in cooperation with the German Aerospace Center (DLR) a full inorganic insulation material with high performance qualities.

Pillow Plate-Heat Exchanger

Currently, pillow-plate heat exchangers (PPHE) enjoy growing attention and become increasingly employed in various branches of industry. The ongoing expansion of the PPHE exploitation area generates a need for new structural requirements for this type of equipment.

Pillow-Plate Heat Exchanger

The use of pillow-plate heat exchangers in process industries has been continuously increasing. Usually, the heating or cooling medium flows through the inner channels of the pillow plates, while the process medium flows through the outer channels.

Mutation Detection in ctDNA or CTC

Particularly in oncology, determination of gene mutation statuses serves as a biomarker to guide rational therapeutic decisions. Due to patient safety sequential biopsies or biopsies of multiple tumor lesions are not routinely performed.

IAP

Scientists of the FH Münster developed several novel intrinsic antimicrobial polymers. State of the art antimicrobial polymers are polymers with antimicrobial additives such as silver or copper.

A Novel Marker for Brown Fat Activity

Brown adipose tissue (BAT) is a special type of fat, which regulates the body temperature by fatty acid oxidation.

Multiphase Loop Reactor

Bioreactors and fermenters are often used in a multiphase design. The mixture of the phases leads to the development of foams and emulsions that cannot be separated afterwards.

Food Quality Control

Food with high sugar content is prone to contamination with yeasts that have a high osmotic tolerance. This contamination leads to a shortened storage life and a loss of quality.

Blockage-free cross-vortex air nozzle

Systems for the separation of material flows have slotted nozzles that generate a homogeneous fluid velocity field.

Pain-Vis

Pain is probably the most common symptom and sensation of a disease, and a big individual and socioeconomic challenge.

Welding of FRP and metal

The increasing trend towards lightweight constructions, especially in the aerospace sector and in automotive production requires the use of new technologies, manufacturing processes and materials.

Flexible electric screwdriver

Cordless screwdrivers are nowadays must-have components for any professional craftsman as well as for private do-it-yourself projects and repairs.

Separation of Itaconic and other Dicarboxylic Acids

The annual production of dicarboxylic acids such as itaconic acid, a promising platform chemical derived from biomass, is about 80,000 t.

AGIDC

Due to the increasing number of decentralized power feeder it becomes more and more difficult to keep up the stability of the power grid.

OPoLiCom

Power Line Communication (PLC) is a data transmission technology, which plays an increasingly important role due to smart metering.

MOD-FC

A modern fuel cell is usually made of a stack of individual cells that are mechanically pressed together.

Li-Booster

Scientists at the MEET battery research center at the Westphalian Wilhelms-University of Muenster have invented an electrolyte additive for the formation of a stable SEI film (SEI = solid electrolyte inter-phase) on anodes for lithium-ion batteries.

E-Lumi-Tex

Researchers of the Niederrhein University have invented a method to produce electroluminescent textile surface by conventional printing methods.

P2Y 12-receptor antagonist

Purinergic receptors have been in the focus of drug discovery for many years. Modulation of P2 receptors in platelets is of paramount importance in regulating platelet function, and as a consequence, in controlling thrombotic diseases, which are the most common cause of morbidity and mortality in the Western world.

Overlap Fix

Due to the limited needle shifting in state of the art weaving systems, current textile products present many limitations regarding their effectiveness and lifetime.

Extracellular production of designer HAAs

One important biosynthetic precursor of fatty alcohols is hydroxyalkanoyloxy alkanoic acid (HAA). HAA can be produced by microbes using sugars as substrate.

Enzymatic Bio-Coating

Biological coatings have a high potential for manifold applications, especially for medical applications or biodegradable coatings.

Envirostat: Single Cell Analysis

The here presented technology allows to separate polarizable bioparticles, such as bacteria, from each other and to cultivate them individually under controlled environmental conditions.

HISEC-GKM

Authorities and organzisations with security tasks (BOS) require wireless communication systems that guarantee a particularly high degree of reliability against unauthorized interception or even manipulation of transmitted data by third parties.

Orthodontic Duplex Pliers

In orthodontics, there is a multitude of intraoral devices and wires that can be activated by bending. However, due to restricted access, wire bending is often difficult if not impossible, especially in the palatine region and lingual of the mandible.

Induced Somatic Stem Cells

Since the pioneer work published by Takahashi & Yamanaka, the technique of reprogramming cells from a differentiated to an embryonic-like status has experienced an exploding development in regard to both techniques and applications.

CAAI - Covalent-allosteric AKT inhibitors

The development of new drugs in oncology has shifted from unspecific cytotoxic drugs to highly specific substances with known targets and modes of action.

Parthenolide and its derivatives for use in the treatment of axonal damage

Peripheral nerve damage is a common cause of considerable functional morbidity, and healthcare expenditure.

CorA as an effective therapeutic agentkor

Dirofilariasis is caused by Dirofilaria immitis and D. repens, parasitic nematodes transmitted by mosquitoes. The heartworms harbour the bacterial endosymbionts Wolbachia, which are essential for worm development, fecundity and survival.

NHR2 inhibitors

The formation and onset of the prevalent form of acute myeloid leukemia (AML, FAB subtype M2) requires RUNX1/ETO, the product of the t(8;21) chromosomal translocation.

EMULSION BUSTER 2.0

A process for an efficient phase separation of emulsions resulting from biphasic whole cell-bio-transformations has been developed at the TU Dortmund.

Delta-Sensor

Corrosion of steel in concrete or steel pipelines embedded in the ground is a global problem, leading to billions of dollar of consequential losses. A reliable diagnosis of the condition is the basis for an effective life cycle management.

Cure for CLL

Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in Western countries. The disease is very heterogeneous with some patients showing extremely slow progression while others proceed rapidly into advanced disease stages and require immediate treatment.

Druggable oncogenic fusions

Cancer patients frequently bear therapeutically relevant genome alteration. For instance, lung adenocarcinomas of patients that have never smoked carry genome alterations affecting kinases, such as EGFR mutations and translocations affecting ALK, ROS1 and RET genes.

Multifunctional Aptamers

Targeted therapy has become a promising therapeutic approach within the last decade due to its reduced toxicity. However, further development of targeted approaches for the specific delivery of therapeutically active substances is required.

SWEETNANO

The presented technology is a newly developed sucrose supported synthesis of transition metal doped zinc oxide nanoparticles, which can be used as active material for the fabrication of high capacity anodes for lithium-ion batteries.

Epigenetics in AML

DNA-methylation (DNAm) of CpG dinucleotides is a key epigenetic process. Upon cell division, the DNAm pattern is maintained on the newly synthesized DNA strand by DNA methyltransferase 1 (DNMT1), whereas DNAm pattern changes are triggered by DNMT3A and DNMT3B that act as de novo methyltransferases.

Determination of the Biological Age

Biological age is influenced by parameters, such as genetic background, disease and lifestyle. Currently, the biological age can be assessed by measuring telomere length, DNA rearrangements or protein alterations.

Ang-2

Over the last couple of years the overall survival time of patients with metastatic colorectal cancer (mCRC) has increased significantly due to the development of novel therapeutic strategies.

FoBT Sensor

Zugeschnitten auf die Anforderungen aus der Praxis wurde am Institut für angewandte Nano- und optische Technologien der Hochschule Niederrhein (iNano), Krefeld, der FoBt Sensor weiter entwickelt.

ALXAN

Adenosine is a modulator of many physiological and pathophysiological processes in the central nervous system (CNS).

Vibration sensor

The vibration sensor works with two optical fiber sensors with Bragg gratings, in combination with a bending beam and a broadband light source.

Process to produce fiber composite components

For a cost-efficient mass production of fiber composite components, it is essential to optimize the preparation of the near-net-shape textile preforms.

Exosomes

Exosomes are nano-sized, secreted cell organelles that are released by a huge variety of different cell species, including mesenchymal stem cells (MSCs). Containing a combination of lipids and proteins as well as RNAs, exosomes participate in intercellular communication processes.

Li-Bx

Scientists at the MEET battery research center of the WWU Muenster and the Jacobs University Bremen have invented several new conducting salts for electrolytes. These show remarkable properties when used in lithium-ion batteries.

CCPC

Continuous countercurrent centrifugal partition extraction is a special type of countercurrent extraction and is used for purification of mixtures.

CorA as anthelmintic (Human filariasis)

Human filariasis (elephantiasis and river blindness) is caused by the nematodes W. bancrofti and O. volvulus, transmitted via blood sucking insects.

C4 plant selective herbicide

Weed infestations cause considerable crop yield losses worldwide. C4 weeds like Black-Grass, Cleavers, Green foxtail, Kochia and Barnyard Grass reduce yields of important C3 cereals such as rice, wheat, barley and oat.

SMART-WindEnergy

Our society’s increasing energy demand requires a high degree of uninterrupted utilization of power generation plants.

Li-Protect

Scientists at the Westphalian Wilhelms University of Muenster and the Jacobs University Bremen have identified and synthesized substances that prevent an overload of lithium-ion batteries.

Dual intercalation secondary battery

The here presented technology offers electrochemical energy storage cells, in which positive and negative ions can be intercalated into both anode and cathode respectively.

Anode Material for Lithium-Ion Batteries

The herein presented invention provides a method for the preparation of a cobalt oxide-carbon composite and its application as active material in electrodes for lithium-ion batteries.

Senescence-Methylation-Signature

Long-term culture associated changes need to be considered for quality control of cell preparations. The invention discloses a simple method to track cellular aging based on continuous DNA-methylation changes at six specific CpG sites.

Bose-Einstein-Light (BEL)

Lasers as sources for coherent and intense light are used in many high-tech applications and medical devices. Generally, the generation of Laser-light is characterized by a significant level of optical and electrical energy input and low efficiency.

Diabrux

The invention discloses a device for the quantitative diagnosis of bruxism, thus allowing to determine the degree of bruxism activity.

RODental

RODental is a dentistry cement containing encapsulated phase-change material.

FMED - Fluid matrix authentic substance scent source

The FMED Invention describes a preparation of moderately volatile organic explosives (e.g. TATP) in a fluid matrix. This solvent is chemically inert and olefactorically neutral.

TetGal

Scientists at the University of Bielefeld successfully synthesized tetrakis(perfluoralkyl)gallate, tetrakis(perfluoralkenyl)gallate, and tetrakis(perfluoralkinyl)gallate

Restricting the working area of mobile robots

Users of mobile robot systems often want to restrict the working area of their mobile robot, such as vacuum cleaner robots or intelligent helpers with gripper arms.

On the trail of plasma

Plasmas are used in a wide range of technical applications, including semiconductor technology. Plasma etching and plasma-induced material deposition are used to remove functional layers in a structured manner or to selectively generate surface hardening, cleaning and activation on the target surface.

Oil float

Previous solutions or approaches to the elimination of oil spills on water surfaces consist either of actively working pumps, chemicals or materials that absorb the oil and then have to be cleaned or disposed of.

MRGX2 Receptor Antagonists

G protein-coupled receptors (GPCRs) are the largest group of membrane receptor proteins and represent the most successful targets of drug therapy.

DC-DC resonant converter

Flexible chargers for batteries (especially in the field of e-mobility), fuel cell applications or flexible photovoltaic battery combinations all contain switch-mode power supplies with DC converters, DC-DC converters in short.

Method for current measurement in half-bridge topologies

A number of different instrument transformers are used to determine voltage and current in regulated power electronics. Current measurement becomes more and more difficult with increasing current intensity, especially since the switching frequencies increase due to the use of modern (e.g. GaN) transistors and parasitic properties of the sensors must be minimized.

Split Inteins Without Active Site Cysteine

Inteins are protein domains that auto-catalyze protein-splicing of their flanking regions with a peptide bond.

GridMaximizer

The electrical power grid is undergoing a major transformation. Increasing numbers of decentralized feeders have been added in recent years and, in the future, there will be a large number of charging stations for electric vehicles that temporarily draw a large amount of electrical power from the power grid.

Charge-Sensitive Amplifier

The charge-sensitive amplifier is an electronic circuit for amplifying the lowest voltages. It is suitable for the usual applications of an electrometer.

Fault Identification in DC Grids

The proportion of electricity generated by renewable energies is growing steadily, as is the proportion of DC power in the energy consumption.

Bubble-EX

This invention describes a novel cardiotomy reservoir based on the degassing technology of liquids.

Future Display Technology

The presented technology is a two dimensional optical waveguide with very low attenuation.

Rotating yarn guide

The invention disclosure here describes a traversing device for yarns with which the yarn position can be moved between two end positions.

Weft insertion via rotary roller

The invention disclosed here describes a traversing device for the lateral laying of a yarn for weft insertion in warp knitting machines.

Structured Yarn Coating

This invention describes a spraying process for the structured coating of a yarn with functional materials in a continuous process.

Research Tools

PROvendis offers various research tools containing: Antibodies, Cell lines, Mouse models, Vectors

Plug’n’Control – Device Coupling in the Smart Grid

Plug’n’Control enables the cross-system coupling of devices with control systems in Smart Grids and Smart Homes.

dualMode-Radio

Most current radio transmission techniques use locally generated signals for the demodulation of the received signals. The electronic devices like synthesizers and local oscillators needed for the demodulation are expensive and require much space.

NMDAR Antagonists as new Antidiabetic Medication

According to the International Diabetes Federation (IDF), diabetes affects close to 400 million people worldwide and caused 500 billion Euros in health expenditure in 2013.