Our technology offers from the fields of Applied Sciences and Life Sciences:
Here you will find innovations protected by property rights from the universities of North Rhine-Westphalia and other research institutes, selectable by technological field. All technologies were evaluated for commercial feasibility and patentability.
Regardless of your own R&D activities you can acquire interesting innovations and thereby minimize the economic risk to your business. In case of interest we can connect you with research partners for successful collaboration.
Piracy protection at the highest level
Physically Unclonable Functions (PUFs) are unique, hardware-based security features that enable secure authentication. Inventors at Ruhr-Universität Bochum use a mm-wave radar system that is guided past a PUF material and the reflection signal enables the PUF material to be uniquely identified.
SelectCells
Extremely mild, selective and efficient technique for separating cells based on temperature-sensitive polymer coating, particularly stem and iPS cells.
Precise photoacoustic gas sensor
The quantitative verification of specific gases in a mixture is technically challenging, so microsystemic sensors often return large measurement errors. A new miniaturized photoacoustic gas sensor from the Technical University of Dortmund can help by detecting target gases very precisely and selectively. A gas sample is radiated from a pulsed light source of suitable wavelength, heating the gas molecules to the proper absorption band.
Multiple Tones Extension (MTE)
Wireless systems are used not only for communication, but also for such secondary applications as localization. In recent years, the cost advantages of Bluetooth indoor localization systems in particular in such areas as asset tracking have led to great popularity.
Treatment of ocular hypertension
Increased intraocular pressure (IOP), also known as ocular hypertension, is widely associated with open-angle and narrow-angle glaucoma. These servere eye diseases may lead to blindness. Current therapeutic approaches use carbonic anhydrase inhibitors (CA Inhibitors), beta blockers, alpha2-receptor agonists, prostaglandins and cholinergics.
Non-invasive glucose measurement
Regular blood sugar measurement is important for diagnosing and treating diabetes mellitus, a metabolic disorder characterized by high blood sugar. Blood sugar can be measured in a variety of ways, but the current method of choice is invasive: a small blood sample to determine sugar concentration.
Optical magnetometer current measuring system
Optical current measuring systems are one way of measuring electric current touchlessly and contactlessly. They use light to determine current precisely. The advantage is that optical transformers are compact, saturation-free, linear, and high-precision. They can detect very large and very small currents in a broad frequency range.
Diagnostic tool for plasma processes
Low-temperature plasmas are used in semiconductor and medical technology and surface engineering. Production process precision and production reproducibility are a growing challenge, especially in semiconductor technology, where components are becoming increasingly smaller.
Active interference-suppressed power electronics
High-frequency circuits can cause electromagnetic emissions that impair other electronic systems. In power electronics, it is therefore often necessary to suppress EMC interference by such means as active narrowband filters.
Photocage Cap for mRNAs
Almost all eukaryotic messenger RNAs (mRNAs) are modified at their 5'-ends by a cap that is synthesised by addition of a 7-methylguanosine attached via a 5'-5' triphosphate bridge to the first transcribed nucleotide of the mRNA chain.
KatTex
Industrial filter bags with catalytic properties are state of the art. They consist of a multi-layer fabric, containing catalytic particle in the intermediate space. Due to this construction, there is a huge pressure lost and cost for an additional fabric layer.
3D ambisonic microphone
Home theater, gaming and VR applications increasingly rely on three-dimensional surround sound, however, low and very low tones in particular are inadequately reproduced.
Artificial Interferons
The invention comprises IFNα2 mutants achieved by designing an IFNα2 with amino acids from IFNα14, which significantly improved their antiviral activity against chronic HBV. As IFNα14 is not suitable for use as a drug, unlike IFNα2, and considering that the IFNα2 mutant is almost as effective as IFNα14, it appears the IFNα2 mutant could be a viable option for clinical application.
PICOihc
The invention pertains to an integrate-and-hold circuit which is used as a sampler. The typical structure of an integrate-and-hold circuit (IHC) is a multiplier serving as a switch followed by a resettable integrator with a hold capacitor.
Retrofit polarization-maintaining in optical fibers (PM)
The invention of the University of Bonn relates to the development of a method to retrofit polarization- maintaining (PM) optical fibers in a way, that a routinated achievement of polarization to a degree better than 10-5 in extinction ratio takes place.
Adaptive Controller
The invention makes optimum use of continuous-value manipulated variables in a closed-loop control system. In this way, the control behavior is improved because the controlled system operates less erratically. As a result, energy consumption and wear are significantly reduced and user comfort is increased.
Antireflective integrated optical waveguide
In transitions between dielectric optical waveguides of different thickness, it comes through modal mismatch usually to radiation losses and optical backscatter.
Air-Retaining-Grids
The present invention "Air-Retaining Grids Technology" describes a new possibility for the architecture and construction of surfaces which are able to keep a layer of gas stable even under changing pressure conditions when immersed in liquid. Structured, non-wettable surfaces are used for various applications, for example as self-cleaning surfaces.
Rotary piston pump
So far, the problem of sealing has been a major challenge when using rotary piston pumps.
TDTO (Three-Dimensional Titanium Oxide)
The present invention belongs to the technical field of rechargeable batteries and supercapacitors. Particularly, it relates to an electrode material for rechargeable batteries and electrochemical capacitors, a method for preparing the same, and rechargeable batteries as well as electrochemical capacitors.
EasyDMEK Shooter and PrepLoad Tool
The invention comprises a DMEK injection device with a special design, which simplifies the release and unfolding of the membrane into the recipient´s eye during surgery. Therefore, the number of subsequent surgical steps and the likelihood of complications is reduced and consequently the success rate of this surgical method is increased. Corneal transplantation is the most successful organ transplantion in medicine and performed on patients with endothelial dysfunction. In a surgery procedure called DMEK (Descemet Membrane Endothelial Keratoplasty), the inner layer of the cornea, the Descemet's membrane, is replaced with a donor membrane. There is also a device for preparing a Descemet membrane endothelial graft and loading an injection or cultivation cartridge.
Combinatory Asthma Endoytping Assay
Asthma is a disease of several subtypes characterized by different severity and a distinct immunological background. Most importantly, several subtypes of allergic asthma need to be correctly identified and distinguished from forms of non-allergic asthma.
Click-Mass Spectrometry of lipids
Aberrations in fatty acid metabolism are associated with pathological states and have become a focus of current research, particularly due to the interest in metabolic overload diseases.
HTRA inhibitors
High Temperature Requirement A (HTRA) proteins are serine proteases of the S1 family (trypsin/chymotrypsin-like). HTRA1 is supposed to play a role in macular degeneration, and HTRA2 has been associated with cell death in reperfusion-ischemia.
Cartilage-specific antimicrobial CLEC3A
Bacterial infection is one of the most frequent complications in joint replacement and dental implant surgery. The incidence of septic arthritis following total joint arthroplasty is approximately 2%, leading to massive health problems and considerable cost to the national economy.
Diagnosis of osteoarthritis
Osteoarthritis (OA) is the most common degenerative disease of joints world-wide. About two-third of people over 65 years are affected, whereas the etiology is largely unclear.
CurrentShare
To reduce the input resistance of power modules, single semiconductor switches are usually connected in parallel.
Brake resistor
To decelerate an electric motor, the remaining kinetic and magnetic energy must be removed from the system. This is usually done with brake resistors that convert the energy to heat.
Cyclic AMP Biosensor
Cyclic AMP is a key molecule in 2nd messenger cell signalling. Great effort has been taken to develop sensors that allow for noninvasive assessment of cAMP concentrations in living cells.
Opto-THC
Sample-and-hold circuits or track-and-hold (TH) circuits, along with analog-to-digital converters (ADCs), are the link from the analog to the digital world.
Novel Anti-Tuberculosis Compounds
The resurgence of tuberculosis, caused primarily by Mycobacterium tuberculosis (Mtb), and the appearance of multi‐drug and extensively drug resistant Mtb strains strengthen the need for new drugs with alternative modes of action.
Novel Markers for Male Fertility Diagnosis
Infertility affects an estimated 15 percent of couples globally, amounting to 48.5 million couples. Forty percent of cases are linked to men. An important factor of male infertility is an insufficient quality of sperms due to abnormal shape and/or motility.
A Multifunctional Linker for CAR T-cells
Chimeric antigen receptors (CARs) have been developed for the molecular engineering of effector T-cells to be used in targeted cancer therapy. CARs consist of the antigen-binding single-chain fragment (scFv) of an antibody fused via a hinge region to a transmembrane domain (TM) and to one or more intracellular signalling co-stimulatory regions.
CEACAM1 antibodies for anti-viral therapy
Cytotoxic CD8-positive T cells constitute the crucial leukocyte subpopulation for a cellular response against viral infection.
WOOD-SPRING
Scientists at the Ostwestfalen-Lippe University of Applied Sciences have developed an inseparable connecting element for panel-shaped lightweight construction elements in sandwich construction, which can be used similarly to flat dowels for classic solid wood materials, including for sandwich elements.
HypoxieFit
Athletes, such as marathon runners and cyclists, often resort to training at higher altitude areas, in order to optimize their endurance. The atmosphere in such locations has lower oxygen content, which forces the human body to compensate for the reduced oxygen uptake by increasing hemoglobin concentration in blood.
WiMDaD Wire Mesh Damage Detection
Composite materials are nowadays used in many technical fields. Blades of wind power plants or aircraft parts, for example, are made out of these materials.
Full Inorganic Load Bearing Insulator
Scientists of the University of Duisburg-Essen developed in cooperation with the German Aerospace Center (DLR) a full inorganic insulation material with high performance qualities.
A Novel Marker for Brown Fat Activity
Brown adipose tissue (BAT) is a special type of fat, which regulates the body temperature by fatty acid oxidation.
P2Y 12-receptor antagonist
Purinergic receptors have been in the focus of drug discovery for many years. Modulation of P2 receptors in platelets is of paramount importance in regulating platelet function, and as a consequence, in controlling thrombotic diseases, which are the most common cause of morbidity and mortality in the Western world.
Parthenolide and its derivatives for use in the treatment of axonal damage
Peripheral nerve damage is a common cause of considerable functional morbidity, and healthcare expenditure.
Corallopyronin A as antifilarial drug
The novel anthelmintic natural compound Corallopyronin A (CorA) adresses the heartworm disease in dogs caused by the infection of Dirofilaria parasites (D. immitis and D. repens). The invention is in a late pre-clinical stage: Data are available concerning toxicology and pharmacology. A formulation of CorA is also under development. A production process of CorA has been set up.
Druggable oncogenic fusions
Cancer patients frequently bear therapeutically relevant genome alteration. For instance, lung adenocarcinomas of patients that have never smoked carry genome alterations affecting kinases, such as EGFR mutations and translocations affecting ALK, ROS1 and RET genes.
Determination of the Biological Age
Biological age is influenced by parameters, such as genetic background, disease and lifestyle. Currently, the biological age can be assessed by measuring telomere length, DNA rearrangements or protein alterations.
Exosomes
Exosomes are nano-sized, secreted cell organelles that are released by a huge variety of different cell species, including mesenchymal stem cells (MSCs). Containing a combination of lipids and proteins as well as RNAs, exosomes participate in intercellular communication processes.
Corallopyronin A as antifilarial drug
The novel anthelmintic natural compound Corallopyronin A (CorA) adresses Elephantiasis and River blindness caused by the infection with filarial nematodes (mainly by Wuchereria bancrofti, Brugia malayi, Brugia timori and Onchocerca volvulus). The invention is in a late pre-clinical stage: Data are available concerning toxicology and pharmacology. A formulation of CorA is also under development. A production process of CorA has been set up.
Senescence-Methylation-Signature
Long-term culture associated changes need to be considered for quality control of cell preparations. The invention discloses a simple method to track cellular aging based on continuous DNA-methylation changes at six specific CpG sites.
Automatically adapting sole
Scientists at Münster University of Applied Sciences have developed a smart insole for diabetic foot syndrome (DFS) that can prevent the majority of foot ulcers. The air cushion insole automatically detects areas under heavy strain by measuring pressure and relieves them by redistributing the air pressure in the individual air cushions.
OCT scanners with better insights
The invention from the University of Bonn is based on a software-based method for determining the autofluorescence of the fundus of the eye using optical coherence tomography. By integrating the software, manufacturers of OCT scanners can both significantly expand the range of functions of their devices and reduce examination times.
Intelligent detection and adaptive mitigation of radio interference with RIS-supported drones
Hamm-Lippstadt University of Applied Sciences has developed a method for anomaly identification, precise classification and adaptive mitigation measures for radio interference that can detect and ward off attacks. This is interesting for mobility applications (X2X) in cars, among other things.
Measurable latent heat storage systems
Latent heat stores (PCM stores) are heat stores that store a large proportion of the thermal energy supplied to them in the form of conversion enthalpy, the energy required for the transition from one phase (solid/liquid/gaseous) to another. An invention by Westfälische Hochschule and Bochum University of Applied Sciences can determine the stored heat content using piezoelectric elements.
Electronic Bike Stand
Scientists at the University of Wuppertal have developed an electric bike stand for e-bikes that can be integrated into the frame or retrofitted. This guarantees effortless extension and a secure stand, as the bike stand automatically adapts to the terrain. It also serves as an immobilizer and thus as protection against theft.
CCL3-EASER Mouse
The CCL3-EASER (ErAse, SEnd, Receive) mouse is a genetically engineered knock-in model designed to provide unprecedented in vivo resolution of CCL3 expression and signaling dynamics.
Monitor casing deformation
In everyday life, battery housings must reliably withstand high mechanical and thermal loads during operation. A new invention from TH Köln can reliably detect damage to these surface structures at an early stage using a two-dimensional system of bending sensors made up of diodes.
Recyclable polymers
The technology presented here enables the environmentally friendly production and complete recycling of polymers through targeted depolymerization. In contrast to conventional recycling processes, it allows a loss-free return to monomers and thus a true circular economy - without any loss of quality. This innovation offers companies a sustainable solution for reducing CO₂ emissions and complying with growing regulatory requirements, such as the EU Green Deal. Particularly suitable for sectors such as automotive engineering, electronics and medical technology, it makes a significant contribution to the decarbonization of the plastics industry.
Fabric valve leaflet (ribbon valve leaflet)
The University Hospital Aachen has developed a new type of heart valve prosthesis for implantation in the human or animal body. The valve prosthesis consists of a valve stent with a ring-shaped, lower valve base and a valve leaflet consisting of one or more ligament tissues. The tissue made of polymer threads serves as the basic biomechanical structure for the formation of artificial valve leaflets for heart and venous valves.
Efficient Hydrogen Production
Innovative materials for sustainable hydrogen production: Scientists at Ruhr-Universität Bochum have developed a high-performance NiCoFe alloy that significantly improves the efficiency and stability of alkaline water electrolysis. With low overpotentials and high resistance to reverse currents, this material offers new prospects for the decarbonization of energy-intensive industries. Thanks to versatile manufacturing processes, the alloy can be used as an anode and cathode and enables more economical hydrogen production - a decisive step towards a green energy future.
Skyrmion defect
In theoretical physics, a model of topologically stable soliton vortices in fields is referred to as a skyrmion. These vortices behave like particles or quasiparticles of finite mass. The invention of the University of Duisburg-Essen describes a static and dynamic method for recording the distribution and movement of a parameter over a sample with quasiparticles, e.g. skyrmions.
FishFlowFilter
Researchers at the University of Bonn and Fraunhofer UMSICHT have developed an innovative microplastic filter that is inspired by nature. The bionic filter system uses a special flow technology to remove over 95% of microparticles from wastewater - without clogging and without filter changes. A smart self-cleaning function ensures efficient and sustainable separation of microplastics.
Test bench for orthoses
Scientists have developed a method and a test stand that can be used to measure the stiffness of orthoses. The test stand makes it easy and convenient to determine and optimize the mechanical properties of ankle orthoses directly in the medical supply store.
Hydrogen free Water2Ammonia
An innovative electrochemical process is revolutionizing sustainable ammonia synthesis: using a palladium membrane as a selective hydrogen bridge, the technology enables an efficient LiNRR reaction with water as the hydrogen source. Compared to conventional methods, the system increases NH₃ production by 200% and offers an environmentally friendly alternative to the energy-intensive Haber-Bosch process. Ideal for applications in the chemical industry, the hydrogen economy and sustainable chemical synthesis.
Polymer Wound Dressing
The treatment of chronic and infected wounds remains a major challenge in the healthcare sector. A new development by the University of Siegen and the Amsterdam University Medical Center now offers a promising solution: a therapeutic hydrogel with antimicrobial properties that combats infections - including those caused by multi-resistant bacteria - and detects them at an early stage. This safe, effective technology could revolutionize wound care and significantly improve the healing process.
Sustainable construction/insulating material
Traditional concrete components and insulating materials often require a lot of energy to produce. A new material from the University of Bonn could offer a sustainable alternative: Plant fibres made from renewable raw materials such as miscanthus optimize the properties of concrete and insulating materials, reduce CO₂ emissions and can be grown almost anywhere. An environmentally friendly solution with great potential for the construction industry!
Hydrophobing products from renewable raw materials
An innovative insulation solution based on renewable raw materials such as miscanthus (Chinese reed) has been developed at the University of Bonn. In contrast to conventional insulating materials made from polystyrene or mineral wool, this material is impressive due to its ecological sustainability, low site requirements and high CO₂ binding. A special hydrophobization process makes the plant fibres water-repellent and therefore economically viable. This technology offers an environmentally friendly alternative with high energy efficiency and broad availability.
Innovative ELISA Assays for Non-Invasive Lupus Nephritis Diagnosis
Currently, Lupus Nephritis diagnosis relies on invasive kidney biopsies, as there is no validated biomarker to detect kidney involvement in Systemic lupus erythematosus. The subject-matter of the invention comprises two ELISA-based tests with antibodies against the guanidylated form of the protein YB-1 (YB-1-2G) in serum levels: one to detect YB-1-2G and another to identify autoantibodies against YB-1-2G. These innovations offer significant value by enabling a reliable, non-invasive and valuable addition to early diagnosis of Lupus Nephritis, thereby improving patient care.
TrustFix
Trustfix is the first to offer an algorithm that can be used to securely delete data in a blockchain.
HairProtectColour
Scientists at the Niederrhein University of Applied Sciences have developed a revolutionary hair care formulation: Lignin particles provide UV protection, condition the hair, absorb excess sebum and enable reversible color changes - sustainable and versatile.Added value: Protects, conditions and temporarily colors the hair, combined with environmentally friendly clean beauty technology for everyday and professional applications.
Affordable rectifier circuit
Rectifier circuit with high efficiency and only two semiconductor switches: An invention from Bielefeld University of Applied Sciences has realized a pulse rectifier with only two semiconductor switches that can be switched off and an electrically isolated DC output voltage. The level of the DC output voltage is freely selectable and the circuit concept is cost-effective and robust.
Circular RNA
Scientists of the University Hospital Bonn and Stanford University have discovered that mammalian IRES-like sequences can overcome the efficiency limitations of eukaryotic translation initiation in circular RNA therapeutics.
Organo-Metal Composites
With the aid of the invention, sulphur-free coatings can easily be produced on base metal surfaces. This makes functionalized surfaces accessible, e.g. for sensors etc.
Three-phase electrode
The invention enables non-destructive, electrochemical conversion to organic compounds such as carbonyl compounds and alcohols with high energy efficiency and high current densities. This should enable the electrochemical refining of biomass.
Mouse models for haematopoiesis and deafness
Mouse models for studying hematopoietic differentiation without severe systemic effects. Mouse models suited for research focusing on erythroid and megakaryocytic lineages. Mouse models for studying defects in granulocyte development and inner ear hair cell biology, in particular deafness. Mouse models with GFP reporter gene additionally available.
GSDMD VHHs prevent pyroptosis
Single domain antibodies (sdAbs) against GSDMD prevent pyroptosis, GSDMD pore formation and IL-1β release. sdAbs act intra and extracellularly.
High-voltage macro cell
A new type of high-voltage macrocell from Dortmund University of Applied Sciences and Arts makes it possible to store energy with a total voltage of up to 20,000 volts. For this purpose, individual modular storage modules (“FOXe”) with a voltage of up to 1500 volts are joined together in tube systems to form a high-voltage macrocell.
THz Receiver Circuit
The University of Wuppertal has developed a novel and compact receiver circuit for THz radiation. This is suitable for use in receiver arrays and can be integrated on silicon-based chips in CMOS or silicon-germanium bipolar transistor processes.
Mitigate radio jamming cyberattacks
Driver assistance systems and automated vehicles offer numerous advantages - but the technology also harbors the risk of cyber-attacks that can hinder communication and jeopardize safety. A process has been developed at Hamm-Lippstadt University of Applied Sciences to detect and mitigate radio jamming in good time.
Rotor blades for low wind speeds
A rotor geometry modeled on maple seeds has been developed that enables more efficient operation of wind turbines and fans. It is a geometry that is easy to manufacture and cheaper to produce than conventional rotor blades.
GaN GIT driver circuit
A new gallium nitride driver circuit allows inverters and frequency converters to switch faster, enabling more efficient power electronics that can switch in the MHz range. The advantage of the new GaN driver circuit from Bonn-Rhein-Sieg University of Applied Sciences is that lower losses occur and higher power densities are achieved.
Fin plate
The device is particularly advantageous for the transportation and assembly of wind turbines. Vortex-induced vibrations are significantly reduced or avoided. In principle, the device can be used for all cylindrical structures (e.g. pillars) that need to be protected from vortex-induced vibrations.
Rain gutter water level monitoring
Gutter blockages caused by leaves, dirt and other debris can prevent the flow of water in the gutter, which can lead to considerable damage and problems. Water can spill over the sides of the gutter, causing water damage to the foundations or other parts of the building. In addition, standing water in the gutter can attract insects such as mosquitoes and serve as a breeding ground. In colder climates, the accumulated water can freeze and form ice dams that damage the roof or the gutter itself. Researchers at the University of Siegen have found an innovative solution to this problem by equipping the gutters with a water level sensor.
Procedure for orienting X-ray units
A new technology from Heinrich Heine University based on machine learning (MI) allows X-ray equipment to be automatically adjusted to the respective patient, regardless of the patient's position angle.
Seal effectiveness doubled
The sealing concept consists of two independent seals. This provides additional safety. The gaskets are particularly suitable for plastic flanges. Only low forces are required and leakages are avoided. Extensive measurements have already been carried out.
Supplements for T Cell-Based Immunotherapy
Optimized conceot for the activation of CAR T cells and prevention of exhaustion in the treatment of cancer.
Ü- Fix
In Germany alone, the annual healthcare expenditure for diabetic foot syndrome (DFS) is around 2.5 billion euros. Thanks to a new invention, it is now possible to replace the commercially available solutions for foot pieces, which are not optimally adapted to the needs and mobility requirements of patients, with a foot piece for the external fixator, which mechanically bridges the damaged area or fracture in such a way that the loads are applied proximally at this point during movement. The patient can now be mobilized directly regardless of the healing status.
Magnetic field focusing
Thanks to an invention by Bielefeld University of Applied Sciences and the use of a specially shaped ferrite sheath, the temperature distribution of induction hobs can be made more homogeneous and energy efficiency increased.
Feedback mechanism for powder inhalers
Correct use of capsule-based powder inhalers increases the effectiveness of the active ingredient. Thanks to the new technology for measuring the flow rate and duration of inhalation, the user receives rapid feedback on the quality of inhalation and can adjust their behavior.
Implantable glucose sensor
The innovative glucose sensor makes it easier for patients to measure their blood glucose. It can be implanted and can remain in the body for a longer period of time. The encapsulation of the sensor due to the foreign body reaction does not interfere with the measurement and reliable results are provided at all times.
Quick, low-cost refractometer
In order to adapt optical systems and lenses precisely to an application, it is necessary to know the material properties and the optical parameters of the lens material. A new method developed by Düsseldorf University of Applied Sciences determines the dispersion (wavelength dependence of the refractive index) using a simplified setup without moving parts and even without a wavelength scan.
5-HMF biopolymers
The present invention relates to polymers from renewable raw materials, as well as monomeric precursors for the production of furan-containing polymers and a production process of both the polymers and the precursors. The 5-HMF derivatives serve as monomers for, among others, biodegradable polyesters, polyamides, polyimines and polyurethanes.
Injection unit for micro injection molding
Thanks to a new type of integration of the shut-off needle into the injection plunger and clever guidance of the plastic melt, the production of miniature and micro components becomes more economical and energy-efficient.
Virtual spatial boundaries for robots
Navigating robots safely through spaces - the new technology from Bielefeld University can contribute to this by simply capturing virtual spatial boundaries. The soft-based input of 3D workspaces is thus greatly simplified by augmented reality.
Temperature compensation for semiconductors
The technology of the Ruhr-Universität Bochum is a method for minimizing temperature and tolerance effects in MOS circuits, which can be used in series production for all known analog MOS circuit arrangements. Central parameters such as current consumption, dynamic ranges, gains, 1/f input noise and also the frequency responses can be kept constant.
Phytic acid coating
A new invention from the Hochschule Niederrhein encompasses an environmentally friendly binding agent consisting of alkyl phytic acid oligomers, which can be thermally combined with such substances as epoxy resins (as amine substitutes) and OH-functional binding agents (as crosslinkers).
Climate-neutral steelmaking
Novel raw material input for the production of green steel. In addition to hydrogen, a carbon-containing aerosol is used to produce green steel.
Scalable photodetector
Most optical sensors require an external supply voltage - not so the novel scalable photodetector from the University of Duisburg-Essen. This photodetector can also be processed or manufactured on a foil basis using the MOCVD process. Possible applications include implants without a battery for medical technology.
Greatly improved radar/lidar sensor
Greatly improved distance measurement with radar/lidar sensor through the use of quantum technology. An invention of the University of Paderborn improves radar/lidar systems theoretically up to the resolution limit. Quantum mechanical effects are used here by superimposing several optical signals on a so-called quantum pulse gate (QPG).
ITIH3 - a biomarker for Myasthenia gravis activity
The invention aims at monitoring inter-alpha-trypsin inhibitor heavy chain H3 (ITIH3) in the serum of Myasthenia gravis patients as the first biomarker for the assessment of MG disease activity in clinical routine, e.g. for therapy adjustments. Monitoring can easily be made by quantitative ELISA in routine blood collection. This approach provides objective results, excluding time-of-day dynamics and subjective symptom burden of patients or examiners.
Green Electrodes
Metal free, printable electrode based on an organic compound prepared by polymerization of triaryl amine.
Polymer GRIN
The invention describes a new manufacturing process for GRIN plastic optics, in which extruded films with a defined refractive index gradient are rolled up and sintered. This makes it possible to manufacture lenses with any aperture and adjustable refractive index variation.
Smart power cable monitoring
What is the status of the power cables at the distribution grid level? This information is generally not gathered, since conventional methods such as dissipation factor measurement involve a great deal of effort – and then there are the high costs and power disruption for connected customers.
E-Walker
Walkers are a great help for elderly or temporarily gait-impaired people. However, if the forces are overestimated, the E-Volator from the Ruhr West University of Applied Sciences can lower a stand plate, the person can climb on and then drive electrically and power-saving to their destination.
Wiegand position encoder with Gray code generation
A new technology from the FH Aachen describes a rotation angle sensor for determining the absolute position by means of several Wiegand sensors. The transitions detected by the Wiegand sensors are used in an evaluation circuit to represent the angle of rotation in a Gray code.
EPIC spectrometer
Spectral analysis is used in many areas of measurement technology. But it often requires very large, expensive devices.
MultiXQuant
New analytical method for quantification in lightweight materials such as plastics, polymers or refuse-derived fuels using X-ray fluorescence analysis.
Thermoelectric water heat pump
With the new thermoelectric water heat pump, drinking water can be heated to the desired temperatures in an energy-saving manner. For this purpose, the energy is extracted from heating water with a low flow temperature, which has been heated by means of solar thermal energy, for example, and fed to the drinking water to be heated.
Thermoelectric exhaust-air heat pump
With the new heat exhaust pump, the heat of a ventilation system can be efficiently recovered by means of thermoelectric elements. The heated fresh air can also be heated via the temperature of the exhaust air. The exhaust air heat pump is also suitable for cooling buildings.
Wireless water leakage detection
The battery- and wireless sensor system from the University of Paderborn detects water leaks in buildings, heating systems or the water supply. The permanent and maintenance-free monitoring of bathroom seals, washing machines, basement rooms as well as any kind of water-bearing pipes can be realized reliably and cost-effectively.
Synthetic Cytokine Receptors
Synthetic cytokine receptors (SyCyRs) enable defined background-free cellular responses through addition of synthetic ligands. The system allows the engineering of highly specific amplification or eradication switches for recombinant cells.
Optimized radial compressor
Moving blades can be used in compressors, superchargers and exhaust gas turbochargers to increase overall efficiency by extending the operating range. This new technology was developed at the University of Duisburg-Essen and can be used across all industries.
Efficient fuel cells
The efficiency in fuel cells can be increased by using the waste heat of the fuel cell and the pressure energy of the hydrogen tanks. A system module consisting of a turbine with generator and a heat exchanger can significantly increase the overall efficiency of the process in the fuel cell.
Optical magnetometer
The invention can optically measure magnetic fields with high sensitivity and can be used, among other things, for soil investigations, navigation systems or material investigations. The method from the University of Siegen can also be integrated into existing fluorescence microscopes.
Movement optimization training tool
In order to optimize movement execution, athletes need feedback on their own movement progress. This technology can increase both effectiveness and efficiency through an extended reality (XR)-based approach using real-time feedback.
Monitoring of hemophilia
The invention relates to PD1 as a biomarker for monitoring immune tolerance of coagulation factor VIII treatment of hemophilia A patients.
Vector spectrometer
An improvement in high-resolution gigahertz and terahertz spectroscopy, now enables sensitive measurements of high-frequency signals over a wide spectral range. The application areas for this technology are in chemical analysis as well as quality control: The sensitivity in the measurement of analysis samples with high-frequency signals can thus be significantly increased.
Chromosomal rearrangements in lung cancer
The invention allows to predict tumor responsiveness to FGFR inhibitor treatment, hence, it can serve as a diagnostic tool to guide personalized precision medicine in cancer treatment.
SafeGuard-BR system
The lockable intubation adapter system allows hygienic, protected performance of intensive-care examinations without releasing infectious aerosol particles or droplets into the ambient atmosphere.
Selective ion storage
The measurement of molecular spectra is important for the chemical or pharmaceutical industry. The new method from the University of Cologne is suitable for the acquisition of any kind of spectra of ion species such as rotational, vibrational, Ro-vibrational, electronic spectra. The composition of the spin states of electrons and nuclei can also be determined. This opens up completely new areas of application.
Neurostimulation with light
The stimulation of nerve cells with electrical or optical impulses is a field of research with a multitude of new applications in medicine. In the future, optogenetics will be used to research the healing possibilities of neurodegenerative diseases or traumatic injuries by stimulating photosensitized nerve cells.
String Locks
The tuning stability of stringed instruments - e.g. guitars - depends, among other things, on the fixation of the two string ends. The underlying invention optimizes this by using small clamping components ("bullets") whose use does not require any modification measures and is always reversible. These clamping components thus lead to increased tuning stability in stringed instruments and at the same time to less (time-) consuming string changes. The bullets are used either on the machine head or on the bridge.
Improved satellite navigation
Position determination is of great commercial benefit for motor vehicles in logistics or agricultural technology, among others. A multi-antenna receiver system designed as a ballast at Münster University of Applied Sciences can enable high-precision position determination with conventional GNSS receivers down to a few centimeters.
Wiegand position encoder
Rotary encoders or incremental encoders are used in a wide range of industrial applications. An invention from the FH Aachen makes it possible to measure the angle of rotation or the rotational speed with the aid of a Wiegand sensor, which can be designed as a relative or absolute sensor, and a rotor that can be manufactured at low cost.
Amipysurf
An Invention for prevention of bacterial infection by applying an antimicrobial latex for a surface coating that is mechanically stabilized by chemical or photochemical crosslinking
PLL frequency acquisition
The new and ASIC available PLL circuit of the University of Paderborn can be used in communications or control and measurement technology, especially where a permanent slow sine signal is used e.g. Bang-bang PLL, Hogge PLL, Baud rate CDR, Optical transceivers circuits.
Continuous 3D printing
In order to be able to use 3D printing systems economically and efficiently in series production, the available installation space in the 3D printer must be used optimally for each print or production batch. Thanks to an inclined arrangement of the build platform, the process offers the opportunity to economically mass-produce components despite a high variety of geometries. This is necessary, for example, for medical technology components that have to be adapted to individual structures or body geometry (e.g. dental orthopedics, sports equipment, etc.) and may also have to be fed continuously without batch operation.
Quantum Dot Arrays
Nanostructures are suitable for the fabrication of optoelectronic devices, but their fabrication is costly. Their utility, however, is immense: mode profiles can be created in a direct way, for example, to "attract" lasers or to adjust densities for single quantum dot applications such as single photon sources.
Smart grid expansion
Intelligent power grids can monitor and regulate themselves independently. A new process from the University of Wuppertal makes it possible to stabilize the voltage in grids by installing control units, as well as avoiding overloads.
Photoacoustic gas sensor
Gas sensors are used for the detection of gaseous substances. Resistive measurement methods are often used, but their signal values often exhibit drift due to aging or lose selectivity. A new type of photoacoustic gas sensor (PAS) from the Technical University of Dortmund is different: it detects target gases very precisely and selectively.
Detecting ionizing radiation
Ionizing radiation is harmful to humans and the environment even in the smallest quantities. Therefore, radioactive materials must be continuously monitored in hospitals, mines or reprocessing plants. A novel semiconductor sensor can analyze ionizing radiation in an integrated microfluidic system (in-situ).
Laser absorption spectroscopy
The new method from TU Dotmund uses laser absorption spectroscopy to monitor air quality in order to measure trace gases present, such as methane or CO2. The improved intra-cavity absorption spectroscopy allows the application in measurement technology, industrial process monitoring as well as safety engineering.
Faster MRI examinations
Magnetic resonance imaging (MRI) is an expensive diagnostic imaging examination. A new method developed by the University of Duisburg-Essen significantly shortens MRI examination times by synthetically generating STIR sequences without the otherwise time-consuming STIR scans.
Optical Strain Gauge
The novel and all-optical strain measurement method is highly accurate and cost-effective. The strain is determined by means of an optical fiber-based purely optical method and thus also enables use in harsh application fields, such as explosion-proof areas or where disturbing pulsating magnetic fields interfere with conventional strain measurement sensors.
Diamond Schottky LED
LEDs are used today in a wide variety of applications, including lighting, data transmission, and biological processes. However, the commonly used LED materials are unsuitable for many applications. By using doped diamond, these LEDs can be designed specifically for high temperatures or pressures and especially for applications with special requirements, e.g. in optical metrology.
Vim3 and Mxi-2 antibodies
The invention relates to Vimentin3 and Mxi-2 antibodies found for the non-invasive diagnosis of kidney tumors. These antibodies can make a clear differentiation of oncocytoma and RCC types and allow targeted therapeutic measurements.
Substitute for LIDAR sensors
Optical components like photodiodes have a variety of uses in sensors and telecommunications technology. Even with time-of-flight sensors, the light reflected by objects has to be converted into electrical signals in order to compute the distance or speed of said objects.
Interference filter
Many optical systems, devices and sensors use the principle of interference - an essential factor in the development and optimization of thin-film devices.
OptoRyR
Light-induced opening of the Ryanodine receptor for use as a scalable system in drug screening.
Arylsulfatase A knock-out mice
These mice can be used as a model to study metachromatic leukodystrophy, which is caused by a loss of arylsulfatase A function and consequently by sulfatide accumulation.
Uveal Melanoma Cell Line with monosomy 3
Uveal melanoma is the most common intraocular malignancy. Approximately 50% of uveal melanoma patients die of metastases, which mainly arise from primary tumors with loss of an entire chromosome 3.
Induced Pluripotent Stem Cells (iPSC) of Patients with Heart Diseases
The iPSCs were generated from reprogrammed human dermal fibroblasts. The fibroblasts were derived from patients with heart diseases of distinct genetic background. Controls of healthy volunteers are also available.
Antibody against extracellular matrix (ECM)-components
The polyclonal antibodies are directed against the following proteins of the extracellular matrix: laminin 1, laminin 5, nidogen 1, nidogen 2, cartilage oligomeric matrix protein (COMP).
Antibody against Amyloid-beta phosphorylated at Ser 8 and 26
The antibodies are directed against specific phosphorylation sites of Amyloid-beta at serine 8 or at serine 26, respectively. Forms of Amyloid beta phosphorylated at these serine residue have increased propensity to form toxic aggregates as compared to non-phosphorylated species.
Antibody against the ABD domain of Nesprin-2 Giant
The antibody is directed against the aminoterminal actin-binding domain (ABD) of human Nesprin-2 Giant. Nesprin 2 Giant, also referred to as Enaptin and NUANCE, is involved in the maintenance of nuclear organization and structural integrity.
Antibody against Amyloid-beta nitrated at Tyr10
The antibody is directed against Amyloid-beta, which is nitrated at the tyrosine on position 10. This nitration of tyrosine enhances Amyloid-beta aggregation and plaque-formation.
Novel therapy for Metachromatic Leukodystrophy
The technology relates to a variant of the enzyme arylsulphatase A characterised by increased blood-brain barrier permeability, catalytic activity and half-life, and which is suitable for the treatment of metachromatic leukodystrophy by an enzyme replacement therapy.
Compensating for Leakage current
Efficient charging of traction batteries is a key technology for the success of electric vehicles on the market. To this end, concepts for transformerless on-board chargers are currently being increasingly considered. Interfering high leakage currents to ground can be prevented or compensated for by this invention.
Dummy foot
The invention uses an individualized foot dummy to provide the possibility of examining the lower leg orthosis in order to enable adequate immobilization. To achieve this, the supporting leg is scanned and then additively manufactured in individual parts.
CMOS biosensors
Production process for a highly sensitive biosensor made from a crossed nanowire-structure field-effect transistor. The cost effective CMOS compatible production process allows for e.g. biosignal monitoring of molecules like c-reactive protein (CRP), cardiac troponin (cTnI), electrogenic cells, or peptides such as amyloid-beta.
Smart charging for electric vehicles
There is a growing trend for electric vehicles. Their drive batteries require charging at high power from the available AC power grid. Three-phase on-board chargers (OBCs) are used for this purpose at high power outputs of at least 11 KW.
Lab-on-a-Chip-System
Magnetic particles are often used to transport and/or separate biomolecules such as DNA or proteins. These particles have biochemically functionalized surfaces and are used as markers in analytical biotechnology and medical technology.
New Cryptophycins for ADC and SMDC
The present invention combines new synthetic ways to new Cryptophycin derivatives with alternative conjugation possibilites and pico-molar cytotoxicies, for ADC and SMDC synthesis.
Hydrophobic Phytic Acid Conversion
The innovation presented here concerns the production and use of hydrophobic phytic acid derivatives as an environmentally friendly alternative to conventional phosphate corrosion protection pre-treatments for steel.
Effective hydrogen production
At the Ruhr University Bochum an effective method was developed with which the coating of an electrode can be achieved with high long-term stability, especially during electrolysis such as alkaline water splitting. Due to the coating of the electrode surface with catalytically active material, a significant reduction in the required cell voltage is achieved.
Nano-BioTransporter
Cancer is one of the main causes of death worldwide. One of the newer therapeutic approaches is photodynamic therapy (PDT), a treatment that uses a photosensitizing chemical substance, a particular type of light and oxygen.
Cholinergic activity enhancer
Acetylcholine (ACh) is an essential neurotransmitter with a major function in the central and peripheral nervous system. Furthermore, ACh plays a crucial role in the autonomic nervous system stimulating preganglionic parasympathetic and sympathetic nerve fibres and postganglionic parasympathetic neurons.
Spray freeze-drying
Spray freeze-drying combines the advantageous properties of the well-established techniques spray drying and freeze-drying.
MRGPRX4 Receptor Agonists and Antagonists
G protein-coupled receptors (GPCRs) are the largest group of membrane receptor proteins and represent the most successful targets of drug therapy.
FlexOxy
With extracorporeal membrane oxygenation, the physician only has oxygenators in a few different sizes. A suitable volume would be particularly important for infants and small children in order to relieve the blood circulation.
High-Redshift BODIPY Dyes
Fluorescent molecules are widely used in bioimaging and medicinal applications for several decades due to their high sensitivity and easy visibility.
Plasma Biocatalysis
Enzymatic reactions offer the possibility to synthesize new molecules with high selectivity and turnover.
Extracorporeal apheresis to treat preeclampsia
Pre-eclampsia is caused by an imbalance between the pro-angiogenic factors VEGF and PIGF and the anti-angiogenic factor sFlt-1, because sFlt-1 binds both factors. This binding leads to the inactivation of VEGF and PIGF. The present invention relates to a method by which sFlt-1 is eliminated from blood in an apheresis procedure by passing the blood over a column containing immobilised moVEGF165 or scVEGF165. Simultaneously with sFlt-1 binding, sFlt-1-bound VEGF and PIGF are released so that the angiogenic balance, essential for fetal development, is restored after the return of the two pro-angiogenic factors.
Color flop effects without interference pigments
It is an innovative, cost-effective application method for the creation of color flop effects by means of effect pigments without costly interference pigments.
Determination of the degree of curing of a coating
The method is based on the fact that the polymer network in a cured coating is denser than in a coating that is less cured. It concerns a method by which chemical cross-linking and thus suitability for further processing can be determined for a system of coatings.
Intelligent charging for electric vehicles
Short charging times are essential for the acceptance of battery-powered vehicles. As a result, three-phase on-board chargers are increasingly being installed in electric vehicles as they significantly reduce charging times compared to single-phase charging circuits.
NoFlameSty
Halogen-free polystyrenes that contain flame-retardant components in the polymer chain. These styrene copolymers can be produced synthetically in a batch process using inexpensive raw materials and are characterized by self-extinguishing fire behaviour without the addition of flame retardants. The resulting polymers are completely colorless and odorless and can be extruded and/or foamed using conventional processing methods. If necessary, the fire behaviour can be further optimized by adding flame retardants, depending on the application.
On the trail of plasma
Plasmas are used in a wide range of technical applications, including semiconductor technology. Plasma etching and plasma-induced material deposition are used to remove functional layers in a structured manner or to selectively generate surface hardening, cleaning and activation on the target surface.
Oil float
Previous solutions or approaches to the elimination of oil spills on water surfaces consist either of actively working pumps, chemicals or materials that absorb the oil and then have to be cleaned or disposed of.
MRGX2 Receptor Antagonists
G protein-coupled receptors (GPCRs) are the largest group of membrane receptor proteins and represent the most successful targets of drug therapy.
Method for current measurement in half-bridge topologies
A number of different instrument transformers are used to determine voltage and current in regulated power electronics. Current measurement becomes more and more difficult with increasing current intensity, especially since the switching frequencies increase due to the use of modern (e.g. GaN) transistors and parasitic properties of the sensors must be minimized.
GridMaximizer
The electrical power grid is undergoing a major transformation. Increasing numbers of decentralized feeders have been added in recent years and, in the future, there will be a large number of charging stations for electric vehicles that temporarily draw a large amount of electrical power from the power grid.
Future Display Technology
The presented technology is a two dimensional optical waveguide with very low attenuation.
NMDAR Antagonists as new Antidiabetic Medication
According to the International Diabetes Federation (IDF), diabetes affects close to 400 million people worldwide and caused 500 billion Euros in health expenditure in 2013.