Antibody against the ABD domain of Nesprin-2 Giant
The antibody is directed against the aminoterminal actin-binding domain (ABD) of human Nesprin-2 Giant. Nesprin 2 Giant, also referred to as Enaptin and NUANCE, is involved in the maintenance of nuclear organization and structural integrity.
Amino acids 1-459 of human Nesprin-2 Giant
Electron microscopy, Immunocytochemistry, Immunohistochemistry, Western Blot, Immunoprecipitation
Libotte, T., et al. (2005) Lamin A/C–dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope. Mol. Biol. Cell 16, 3411-3424.