As another advantage over A. terreus, which is also classified as a toxin-producing animal pathogenic fungus in certain countries which is limiting its applicability at industrial scale, the species Ustilago maydis has a history of safe use.
In addition, Ustilago maydis can be easily genetically engineered and grown in liquid culture up to high cell densities and good to handle temperatures of up to 34°C.
On behalf of the RWTH Aachen University, PROvendis offers access to rights for commercial use as well as the opportunity for further co-development.
In case of interest we are pleased to inform you about the current patent status.
E. Geiser et al. (2014); “Prospecting the biodiversity of the fungal family Ustilaginaceae for the production of value-added chemicals.” Fungal Biology and Biotechnology, 1:2
M. Bölker et al. (2015) WO 2015/140314 A1; “Means and methods for itaconic acid production.”