On behalf of the University of Cologne and of the Witten/Herdecke University, PROvendis offers access to rights for commercial use as well as the opportunity for further co-development and evaluation.
In vivo studies have been conducted in mice models of longlasting inflammatory as well as of longlasting neuropathic pain. The tracer is designed to detect pain caused by alterations in the peripheral but not in the central nervous system.
The inventors currently perform a study with patients and have obtained initial positive results.
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Peterson M, Svärdsudd K, Appel L, et al. PET-scan shows peripherally increased neurokinin 1 receptor availability in chronic tennis elbow: visualizing neurogenic inflammation? PLoS One. 2013; 8(10): e75859.