New approaches in alternative energy sources and food production, fermentation processes, modified enzymes for processing technologies – PROvendis offers various biotechnologies for licensing, to purchase or for development cooperation.
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Protective cover made of yeast
Yeast cells are a by-product of beer and bioethanol production and are therefore readily available.
Morphologic optimization of Fungi
Fungi play an important role in biotechnological processes for the production of organic acids, enzymes, antibiotics, polyols, vitamins, (glyco-)lipids, and a wide variety of other secondary metabolites.
Cyclic AMP Biosensor
Cyclic AMP is a key molecule in 2nd messenger cell signalling. Great effort has been taken to develop sensors that allow for noninvasive assessment of cAMP concentrations in living cells.
Biotechnological production of itaconic acid
Itaconic acid is one of the top bio-based chemical building blocks and thus a promising platform compound for the production of polymers, coatings, chemical compounds and biofuels.
Enantiomerically pure chiral N-acyl-a-aminonitriles
Enantiomerically pure N-acyl-a-aminonitriles gained these days interest in the pharmaceutical industry since a range of recently developed pharmaceuticals are based on this product class.
Food Quality Control
Food with high sugar content is prone to contamination with yeasts that have a high osmotic tolerance. This contamination leads to a shortened storage life and a loss of quality.
Separation of Itaconic and other Dicarboxylic Acids
The annual production of dicarboxylic acids such as itaconic acid, a promising platform chemical derived from biomass, is about 80,000 t.
Extracellular production of designer HAAs
One important biosynthetic precursor of fatty alcohols is hydroxyalkanoyloxy alkanoic acid (HAA). HAA can be produced by microbes using sugars as substrate.
EMULSION BUSTER 2.0
A process for an efficient phase separation of emulsions resulting from biphasic whole cell-bio-transformations has been developed at the TU Dortmund.
C4 plant selective herbicide
Weed infestations cause considerable crop yield losses worldwide. C4 weeds like Black-Grass, Cleavers, Green foxtail, Kochia and Barnyard Grass reduce yields of important C3 cereals such as rice, wheat, barley and oat.
New Cryptophycins for ADC and SMDC
The present invention combines new synthetic ways to new Cryptophycin derivatives with alternative conjugation possibilites and pico-molar cytotoxicies, for ADC and SMDC synthesis.
High-Redshift BODIPY Dyes
Fluorescent molecules are widely used in bioimaging and medicinal applications for several decades due to their high sensitivity and easy visibility.
Enzymatic reactions offer the possibility to synthesize new molecules with high selectivity and turnover.
Split Inteins Without Active Site Cysteine
Inteins are protein domains that auto-catalyze protein-splicing of their flanking regions with a peptide bond.