Medical Technology

PROvendis offers innovative medical technologies and products for licensing, to purchase or for development cooperation. The portfolio includes medical devices and complex medical equipment, implants, prosthetic devices, stents, and catheters.

Don't hesitate to contact us! You can also find further contact persons in each technology offer.



Dr. Wolfram Schleich
+49 208 9410535

Non-invasive glucose measurement

Regular blood sugar measurement is important for diagnosing and treating diabetes mellitus, a metabolic disorder characterized by high blood sugar. Blood sugar can be measured in a variety of ways, but the current method of choice is invasive: a small blood sample to determine sugar concentration.

Rotary piston pump

So far, the problem of sealing has been a major challenge when using rotary piston pumps.

EasyDMEK Shooter and PrepLoad Tool

The invention comprises a DMEK injection device with a special design, which simplifies the release and unfolding of the membrane into the recipient´s eye during surgery. Therefore, the number of subsequent surgical steps and the likelihood of complications is reduced and consequently the success rate of this surgical method is increased. Corneal transplantation is the most successful organ transplantion in medicine and performed on patients with endothelial dysfunction. In a surgery procedure called DMEK (Descemet Membrane Endothelial Keratoplasty), the inner layer of the cornea, the Descemet's membrane, is replaced with a donor membrane. There is also a device for preparing a Descemet membrane endothelial graft and loading an injection or cultivation cartridge.

Cartilage-specific antimicrobial CLEC3A

Bacterial infection is one of the most frequent complications in joint replacement and dental implant surgery. The incidence of septic arthritis following total joint arthroplasty is approximately 2%, leading to massive health problems and considerable cost to the national economy.


Careful control of the patient's blood temperature is imperative in cardiac surgery. The heat exchangers used for this purpose are usually integrated in the oxygenator of the heart-lung machine.


Athletes, such as marathon runners and cyclists, often resort to training at higher altitude areas, in order to optimize their endurance. The atmosphere in such locations has lower oxygen content, which forces the human body to compensate for the reduced oxygen uptake by increasing hemoglobin concentration in blood.


Diabrux is a user-friendly and the first bite film validated in clinical studies for the standardised, quantitative diagnosis of sleep bruxism. Diabrux is worn by the patient like a night splint. The device is based on a hard plate, which is covered by five specifically linked layers with different colours and defined abrasion properties. A fully automated evaluation software is provided for standardized, objective, quantitative analysis. Diabrux facilitates monitoring of bruxism activity. Thus, personalized therapy planning is possible and cost-intensive treatments can be scheduled more accurately.

Procedure for orienting X-ray units

A new technology from Heinrich Heine University based on machine learning (MI) allows X-ray equipment to be automatically adjusted to the respective patient, regardless of the patient's position angle.

Ü- Fix

In Germany alone, the annual healthcare expenditure for diabetic foot syndrome (DFS) is around 2.5 billion euros. Thanks to a new invention, it is now possible to replace the commercially available solutions for foot pieces, which are not optimally adapted to the needs and mobility requirements of patients, with a foot piece for the external fixator, which mechanically bridges the damaged area or fracture in such a way that the loads are applied proximally at this point during movement. The patient can now be mobilized directly regardless of the healing status.

Feedback mechanism for powder inhalers

Correct use of capsule-based powder inhalers increases the effectiveness of the active ingredient. Thanks to the new technology for measuring the flow rate and duration of inhalation, the user receives rapid feedback on the quality of inhalation and can adjust their behavior.

Implantable glucose sensor

The innovative glucose sensor makes it easier for patients to measure their blood glucose. It can be implanted and can remain in the body for a longer period of time. The encapsulation of the sensor due to the foreign body reaction does not interfere with the measurement and reliable results are provided at all times.


Walkers are a great help for elderly or temporarily gait-impaired people. However, if the forces are overestimated, the E-Volator from the Ruhr West University of Applied Sciences can lower a stand plate, the person can climb on and then drive electrically and power-saving to their destination.


The advantage is that anesthesiologists have an easy-to-use tool to treat uncooperative or stressed children before anesthesia without sedatives, which can have side effects. There is minimal need to train medical staff to use the new tool. It is cheap to manufacture and without the need for disposable items, which is environmentally friendly.

Total Toe – The foot expander

The "Total Toe", a training device for the toe flexor muscles, can reduce foot amputations for diabetics. Regular training has been shown to counteract muscle regression and reduce peak pressure under the foot - reducing problematic ulcerations and resulting foot amputations.

Movement optimization training tool

In order to optimize movement execution, athletes need feedback on their own movement progress. This technology can increase both effectiveness and efficiency through an extended reality (XR)-based approach using real-time feedback.


This invention provides a sealed respiration system that allows hygienic, protected performance of intensive-care examinations without releasing aerosol particles or droplets into the ambient atmosphere.

Neurostimulation with light

The stimulation of nerve cells with electrical or optical impulses is a field of research with a multitude of new applications in medicine. In the future, optogenetics will be used to research the healing possibilities of neurodegenerative diseases or traumatic injuries by stimulating photosensitized nerve cells.

Continuous 3D printing

In order to be able to use 3D printing systems economically and efficiently in series production, the available installation space in the 3D printer must be used optimally for each print or production batch. Thanks to an inclined arrangement of the build platform, the process offers the opportunity to economically mass-produce components despite a high variety of geometries. This is necessary, for example, for medical technology components that have to be adapted to individual structures or body geometry (e.g. dental orthopedics, sports equipment, etc.) and may also have to be fed continuously without batch operation.

BE-TI Safety Catheter

Completely closed puncture system. The BE TI Safety Catheter System allows a catheter to be inserted faster, safer and with significantly reduced blood loss, can be placed in almost any body position without risk of air embolism, and saves valuable time during emergency procedures.

Faster MRI examinations

Magnetic resonance imaging (MRI) is an expensive diagnostic imaging examination. A new method developed by the University of Duisburg-Essen significantly shortens MRI examination times by synthetically generating STIR sequences without the otherwise time-consuming STIR scans.

Dummy foot

The invention uses an individualized foot dummy to provide the possibility of examining the lower leg orthosis in order to enable adequate immobilization. To achieve this, the supporting leg is scanned and then additively manufactured in individual parts.

CMOS biosensors

Production process for a highly sensitive biosensor made from a crossed nanowire-structure field-effect transistor. The cost effective CMOS compatible production process allows for e.g. biosignal monitoring of molecules like c-reactive protein (CRP), cardiac troponin (cTnI), electrogenic cells, or peptides such as amyloid-beta.


Magnetic particles are often used to transport and/or separate biomolecules such as DNA or proteins. These particles have biochemically functionalized surfaces and are used as markers in analytical biotechnology and medical technology.


With extracorporeal membrane oxygenation, the physician only has oxygenators in a few different sizes. A suitable volume would be particularly important for infants and small children in order to relieve the blood circulation.

Extracorporeal apheresis to treat preeclampsia

Pre-eclampsia is caused by an imbalance between the pro-angiogenic factors VEGF and PIGF and the anti-angiogenic factor sFlt-1, because sFlt-1 binds both factors. This binding leads to the inactivation of VEGF and PIGF. The present invention relates to a method by which sFlt-1 is eliminated from blood in an apheresis procedure by passing the blood over a column containing immobilised moVEGF165 or scVEGF165. Simultaneously with sFlt-1 binding, sFlt-1-bound VEGF and PIGF are released so that the angiogenic balance, essential for fetal development, is restored after the return of the two pro-angiogenic factors.