Uveal Melanoma Cell Line with monosomy 3

Ref.-Nr. 4911

Uveal melanoma is the most common intraocular malignancy. Approximately 50% of uveal melanoma patients die of metastases, which mainly arise from primary tumors with loss of an entire chromosome 3.

Human primary uveal melanoma

Genetic background
Cell line of uveal melanoma with loss of chromosome 3 (UPMM-1) and chromosome isodisomy (UPMM-2), respectively

Donor information
Gender and Ethnicity: Male Caucasian

Research, Drug development

Nareyeck, G., et al. (2006) Establishment and characterization of two uveal melanoma cell lines derived from tumors with loss of one chromosome 3. Exp. Eye Res. 83: 858-864.

Prof. Dr. Frank Entschladen
+49 208 9410520