Uveal Melanoma Cell Line with monosomy 3
Uveal melanoma is the most common intraocular malignancy. Approximately 50% of uveal melanoma patients die of metastases, which mainly arise from primary tumors with loss of an entire chromosome 3.
Human primary uveal melanoma
Cell line of uveal melanoma with loss of chromosome 3 (UPMM-1) and chromosome isodisomy (UPMM-2), respectively
Gender and Ethnicity: Male Caucasian
Research, Drug development
Nareyeck, G., et al. (2006) Establishment and characterization of two uveal melanoma cell lines derived from tumors with loss of one chromosome 3. Exp. Eye Res. 83: 858-864.