Uveal melanoma is the most common intraocular malignancy. Approximately 50% of uveal melanoma patients die of metastases, which mainly arise from primary tumors with loss of an entire chromosome 3.

Description
Human primary uveal melanoma

Genetic background
Cell line of uveal melanoma with loss of chromosome 3 (UPMM-1) and chromosome isodisomy (UPMM-2), respectively

Donor information
Gender and Ethnicity: Male Caucasian

Usage
Research, Drug development

Reference
Nareyeck, G., et al. (2006) Establishment and characterization of two uveal melanoma cell lines derived from tumors with loss of one chromosome 3. Exp. Eye Res. 83: 858-864.